Valproic acid vs Valerian...Food for Thought

Discussion in 'Your Living Room' started by poppaharley, Dec 22, 2008.

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  1. poppaharley

    poppaharley Meniere's: God's answer to a free merry-go-round

    Ya know...... sometimes there are just some coincidences that amaze me.

    Just the other day, "Terri Lee" posts": "Decided to try taking 3 valerian root and have a little lie-down (just 30 minutes) to see if I could fend off the worst of it. Lo and behold, aside from a little dizzyness and foggy eyes for the rest of the night, the attack didn't come........Had a similar occurance today - and once again, the valerian root seemed to tone everything down. I think I might be onto something here!"

    Then the next day, "bnatural" posts: "Does anyone know if Valproic Acid makes the symptoms of Meniere's worse? I recall seeing this somewhere on the web, but I can no longer find the reference."

    and then

    "ifishdizzy" replys: My only exposure to Valproic Acidn (Depakote) was that my first wife took it for epilepsy, but in some Google searches I just read where it is also used in some treatments for Meniere's Disease.

    I googled "Valeric Acid" and find: "Valproic acid (by its official name 2-propylvaleric acid) was first synthesized in 1882 by Burton as an analogue of valeric acid, found naturally in valerian.[1].....In 1962, the French researcher Pierre Eymard serendipitously discovered the anticonvulsant properties of valproic acid while using it as a vehicle for a number of other compounds that were being screened for anti-seizure activity. .....Since then it has also been used for migraine and bipolar disorder.[3]"

    SO...looks like there is certainly a connection between Valerian and Valproic Acid and the fact that Valproic Acid is used for anti-seizure and anti-convulsive agent sure looks like it should have some potential benificial effect for Menieres rather than a negative effect.

    Tony
     

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