If it were completely legalized, perhaps we would stop paying extremely wealthy people with large tracts of land to not grow anything at all. People on this list would include Charles Barkley, Micheal Jackson, and countless others. It may hurt some businesses, but it also will start new ones, and perhaps make it so that we start producing some of these products domestically instead of importing from China. As far as the idea that in 20 years, it will be readily available for medicinal use, That was thought to be true on many occaisions. Every time this has come close, a new breed of fear mongers come in and stopped it. This is true, even though studies have shown that current laws do nothing to stop usage, and those few times that it has been decriminalized in certain areas, usage has not increased. Yes, it was used for it's other properties in the US for a few centuries and in the middle east for a few millinea, it was not until the early 1900's that it was used in the drug sense in the US.